Preventive health behaviours during coronavirus disease 2019 pandemic based on health belief model among Egyptians

BackgroundCoronavirus disease 2019 (COVID-19) is spreading rapidly in the world, and on 11 March 2020, WHO announced the outbreak a global pandemic. Given the severity of this major outbreak and the importance of prevention and protection against the spread of SARS-CoV-2, the predictors of engaging in the preventive behaviours could potentially be of great practical importance as it could help us identify high-risk groups and take the necessary steps towards improving their health behaviour. As the health behavioural response of the Egyptian population during COVID-19 is unknown and the health belief model constructs can be used to explain health behaviour, this study was conducted to assess the preventive behaviours to COVID-19 and the associated role of health belief model constructs over three periods of time;at the beginning of COVID-19 pandemic then 4 weeks and10 weeks later.ResultsPerceived severity and benefits of health belief model constructs showed significant decrease in the 2nd interview, followed by an increase in the 3rd interview (P < 0.001). Perceived barriers showed a significant increase in the 2nd interview followed by a significant decrease in the 3rd interview (P < 0.001). Knowledge score was significantly lower at the start, then a surge happened in the next interview followed by a slight drop in the 3rd interview (P < 0.001). Preventive behaviours were significantly lower in the 2nd interview then significantly higher in the 3rd interview (P < 0.001). On the analysis of the factors associated with preventive behaviours using multivariate regression, the results determined age, high education, being a health care worker, perceived susceptibility, benefits, barriers and self-efficacy.ConclusionsPerceptions of benefits could be increased by tailoring communication strategies to various groups, emphasizing how different people can engage in effective preventive behaviours. Policy makers should pay attention to lower-educated persons living in rural areas being a group with the least engagement in health-protective actions.

Technostress Creators and Outcomes Among Egyptian Medical Staff and Students: A Multicenter Cross-Sectional Study of Remote Working Environment During COVID-19 Pandemic.

Objectives: This study aimed to investigate the technostress creators and outcomes among University medical and nursing faculties and students as direct effects of the remote working environment during the COVID-19 pandemic. Background: Due to the current COVID-19 pandemic, shifting to virtual learning that implies utilizing the information and communication technologies (ICTs) is urgent. Technostress is a problem commonly arising in the virtual working environments and it occurs due to misfitting and maladaptation between the individual and the changeable requirements of ICTs. Methods: A multicenter cross-sectional study was conducted in medicine and nursing colleges of 5 Egyptian universities and included both staff members and students. The data were collected through personal interviews, from January to May 2021. All the participants took a four-part questionnaire that asked about personal and demographic data, technostress creators, job or study, and technical characteristics and technostress outcomes (burnout, strain, and work engagement). Furthermore, participants' blood cortisol and co-enzyme Q10 (CoQ10) levels were tested in a random sample of the students and medical staff. Results: A total of 3,582 respondents participated in the study, 1,056 staff members and 2,526 students where 33.3% of the staff members and 7.6% of students reported high technostress. Among staff members, total technostress score significantly predicted Cortisol level (ß = 2.98, CI 95%: 0.13-5.83), CoQ10(ß = -6.54, CI 95%: [(-8.52)-(-4.56), strain (ß = 1.20, CI 95%: 0.93-1.47), burnout (ß = 0.73, CI 95%: 0.48-0.97) and engagement (ß = -0.44, CI 95%: [(-0.77)-(-0.11)]) whereas among students, total technostress score significantly predicted cortisol level (ß = 6.64, CI 95%: 2.78-10.49), strain (ß = 1.25, CI 95%: 0.72-1.77), and burnout (ß = 0.70, CI 95%: 0.37-1.04). Among staff members and students, technology characteristics were significantly positive predictors to technostress while job characteristics were significantly negative predictors to technostress. Conclusion: The Egyptian medical staff members and students reported moderate-to-high technostress which was associated with high burnout, strain, and cortisol level; moreover, high technostress was associated with low-work engagement and low CoQ10 enzyme. This study highlighted the need to establish psychological support programs for staff members and students during the COVID-19 pandemic.

Potential impact of serpin peptidase inhibitor clade (A) member 4 SERPINA4 (rs2093266) and SERPINA5 (rs1955656) genetic variants on COVID-19 induced acute kidney injury.

Background: SARS-CoV-2 has a number of targets, including the kidneys. Acute Kidney Injury (AKI) might develop in up to a quarter of SARS-CoV-2 patients. In the clinical environment, AKI is linked to a high rate of death and leads to the progression of AKI to chronic renal disease. Aim: We aimed to investigate rs2093266 and rs1955656 polymorphisms in SERPINA4 and SERPINA5 genes, respectively, as risk factors for COVID-19 induced AKI. Subjects and methods: A case-control study included 227 participants who were divided into three groups: 81 healthy volunteers who served as controls, 76 COVID-19 patients without AKI and 70 COVID -19 patients with AKI. The TaqMan assay was used for genotyping the SERPINA4 (rs2093266) and SERPINA5 (rs1955656) polymorphisms by real-time PCR technique. Results: Lymphocytes and eGFR showed a significantly decreasing trend across the three studied groups, while CRP, d-Dimer, ferritin, creatinine, KIM-1and NGAL showed a significantly increasing trend across the three studied groups (P < 0.001). Rs2093266 (AG and AA) genotypes were significant risk factors among non-AKI and AKI groups in comparison to controls. Rs1955656 (AG and AA) were significant risk factors among the AKI group, while AA was the only significant risk factor among the non-AKI group. Recessive, dominant, co-dominant, and over-dominant models for genotype combinations were demonstrated. The GG v AA, GG + AG v AA, and GG v AG + AA models of the rs2093266 were all significant predictors of AKI, whilst only the GG v AA model of the rs1955656 SNP was a significant predictor. The logistic regression model was statistically significant, χ2 = 56.48, p < 0.001. AKI was associated with progressed age (OR = 0.95, 95% CI: 0.91-0.98, p = 0.006), suffering from chronic diseases (OR = 3.25, 95% CI: 1.31-8.01, p = 0.010), increased BMI (OR = 0.89, 95% CI: 0.81-0.98, p = 0.018), immunosuppressive (OR = 4.61, 95% CI: 1.24-17.16, p = 0.022) and rs2093266 (AG + AA) (OR = 3.0, 95% CI: 1.11-8.10, p = 0.030). Conclusion: Single nucleotide polymorphisms (rs2093266) at SERPINA4 gene and (rs1955656) at SERPINA5 gene were strongly linked to the development of AKI in COVID-19 patients.

A cross-sectional study of gastrointestinal manifestations in COVID-19 Egyptian patients.

BACKGROUND: The latest novel corona virus disease (COVID-19) pandemic shows a significant health concern. We aimed to study the prevalence of gastrointestinal symptoms among COVID-19 Egyptian patients. METHODS: A cross-sectional study was carried out on 860 patients with COVID-19 infection classified according to Ministry of Health Program (MOHP) into three groups (280 patients with mild infection, 258 patients with moderate disease and 322 patients with severe disease). All patients were subjected to medical history, clinical examination, laboratory investigations, high-resolution computed tomography chest (HRCT chest) and other investigations when needed in some patients e.g., upper gastro-intestinal (GI) endoscopy, abdomino-pelvic ultrasound and ECHO. RESULTS: Gastro-intestinal symptoms were present in 27.2% of the studied patients. The most common reported GIT symptoms were vomiting, diarrhea, abdominal/gastric pain, followed by nausea. GIT symptoms presence was significantly higher in severe cases in comparison to mild or moderate cases. C-reactive protein (CRP), serum ferritin, Aspartate aminotransferase (AST), bilirubin, and creatinine were significantly associated with the presence of GI symptoms. CONCLUSIONS: GI symptoms are prevalent among COVID-19 patients, the most common were vomiting and diarrhea and were associated with COVID-19 severity.

Prevalence and associated risk factors of cannabinoid abuse among Egyptian university students: a cross-sectional study.

Global surveys have highlighted rise in consumption of cannabinoids among residents of both developed and developing countries. Cannabinoids cause severe damage to the cardiovascular, nervous, respiratory, and renal systems, and have been linked with several deaths. Despite these adverse health effects, the use of cannabinoids has rapidly increased. This work seeks to estimate the prevalence of cannabinoid abuse among Egyptian university students and explore the associated risk factors. A cross-sectional study was carried out over 3 months (1st of July-1st of October 2020) and included 2380 students. Participants were subjected to a pre-designed self-administered questionnaire that included demographic data, Addiction Severity Index, and Depression Anxiety Stress Scale. Among the participating students, 4.9% of them reported cannabinoid abuse and 41% reported smoking cigarettes. The most used substances were hashish (96.5%), Strox (41.3%), Bhang (34.4%), voodoo (34.4%), and Tramadol (31.1%). Gender and social status were also significantly related to rates of substances abuse; most illicit drug users were males (93.1%), and the majority was of low (41.3%) or moderate (50.8%) socioeconomic status. The most significant risk factors associated with substance use were positive history of family conflict (OR=6.48; CI95%: 5.08-8.64, p<0.001), encouragement by peers (OR=2.95; CI95%: 1.73-5.05, p<0.001), male gender (OR=5.46; CI95%: 2.40-12.44, p=0.001), positive history of child abuse (OR=2.85; CI95%: 1.96-3.04, p=0.001), having a stay-at-home mother (OR= 1.56, CI95%: 1.19-2.04, p=0.001), living in an urban area (OR=2.22; CI95%: 1.53-5.0, p=0.002), and positive family history of substance use (OR=1.98; CI95%: 1.48-2.08, p=0.045). This study emphasizes the possible significant rise in substance use among university students. Awareness campaigns should target both students and student families.

Knowledge, Attitude and Practice toward COVID-19 among Egyptians.

COVID-19 is a public Health Emergency of International Concern. The aim of this work was to assess the level of Knowledge, Attitude and Practice (KAP) among Egyptians toward COVID-19. A cross-sectional study was conducted from March 1st to April 1st, on 3712 participants of different ages and sex. An author designed KAP questionnaire toward COVID-19 administered online and personally was delivered. Satisfactory knowledge, positive attitude and good practice were reported among 70.2%, 75.9% and 49.2% of the participants respectively. Middle-aged participants reported high knowledge and attitude levels with poor practice level (p < 0.001). Females reported high knowledge and practice levels and low attitude (p < 0.001 and p = 0.041 respectively). Despite reporting high knowledge and attitude among urban residents (p < 0.001), practice level was high among rural residents (p = 0.001). Post-graduate education reported the highest levels of KAP (p < 0.001). Rural residents, working and non-enough income participants reported lower level of practice (p < 0.001). Logistic regression was carried out. It was found that unsatisfactory knowledge was associated with low education [Odds Ratio (OR) = 1.97, 95% CI: 1.51-2.56], and of rural residency (OR = 1.2, 95% CI: 1.05-1.41). Negative attitude was associated with not working (OR = 1.94, 95% CI: 1.61-2.35) and not enough income (OR = 1.29, 95%CI: 1.10-1.51 respectively). Poor practice is associated with young age (OR = 2.41, 95% CI: 1.94-2.98) and low education (OR = 1.19, 95% CI: 1.03-1.37) and not working (OR = 4.95, 95% CI: 4.07-6.02). Satisfactory knowledge, positive attitude and poor practice were found among the participants. A good knowledge and lower practice level were found among middle-aged, working participants, and participants with insufficient income. The demographic characters associated with KAP could be the cornerstone in directing policy-makers to target the health education campaigns to the suitable target groups.